Title
A Signal Separation Technique for Sub-Cellular Imaging Using Dynamic Optical Coherence Tomography.
Abstract
This paper aims at imaging the dynamics of metabolic activity of cells. Using dynamic optical coherence tomography, we introduce a new multi-particle dynamical model to simulate the movements of the collagen and the cell metabolic activity and develop an efficient signal separation technique for sub-cellular imaging. We perform a singular-value decomposition of the dynamic optical images to isolate the intensity of the metabolic activity. We prove that the largest eigenvalue of the associated Casorati matrix corresponds to the collagen. We present several numerical simulations to illustrate and validate our approach.
Year
DOI
Venue
2017
10.1137/16M1090387
MULTISCALE MODELING & SIMULATION
Keywords
Field
DocType
doppler optical coherence tomography,signal separation,spectral analysis,singular value decomposition,dynamic cell imaging
Computer vision,Optical coherence tomography,Cellular imaging,Biological system,Mathematical analysis,Matrix (mathematics),Artificial intelligence,Mathematics,Eigenvalues and eigenvectors
Journal
Volume
Issue
ISSN
15
3
1540-3459
Citations 
PageRank 
References 
0
0.34
1
Authors
3
Name
Order
Citations
PageRank
Habib Ammari1821104.69
Francisco Romero251.86
Cong Shi311.04