Title
Flexible, Low-Cost Sensor Based on Electrolyte Gated Carbon Nanotube Field Effect Transistor for Organo-Phosphate Detection.
Abstract
A flexible enzymatic acetylcholinesterase biosensor based on an electrolyte-gated carbon nanotube field effect transistor is demonstrated. The enzyme immobilization is done on a planar gold gate electrode using 3-mercapto propionic acid as the linker molecule. The sensor showed good sensing capability as a sensor for the neurotransmitter acetylcholine, with a sensitivity of 5.7 mu A/decade, and demonstrated excellent specificity when tested against interfering analytes present in the body. As the flexible sensor is supposed to suffer mechanical deformations, the endurance of the sensor was measured by putting it under extensive mechanical stress. The enzymatic activity was inhibited by more than 70% when the phosphate-buffered saline (PBS) buffer was spiked with 5 mg/mL malathion (an organophosphate) solution. The biosensor was successfully challenged with tap water and strawberry juice, demonstrating its usefulness as an analytical tool for organophosphate detection.
Year
DOI
Venue
2017
10.3390/s17051147
SENSORS
Keywords
Field
DocType
carbon nanotube,flexible,electrolyte gated transistor,organophosphate detection
Tap water,Immobilized enzyme,Analytical chemistry,Electrolyte,Electronic engineering,Analyte,Carbon nanotube field-effect transistor,Biosensor,Engineering,Carbon nanotube,Electrode
Journal
Volume
Issue
Citations 
17
5.0
0
PageRank 
References 
Authors
0.34
0
4
Name
Order
Citations
PageRank
Vijay Deep Bhatt100.68
Saumya Joshi200.68
Markus Becherer363.59
Paolo Lugli412419.26