Title
Quantitative Evaluation of Temporal Regularizers in Compressed Sensing Dynamic Contrast Enhanced MRI of the Breast
Abstract
Abstract Purpose. Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) is used in cancer imaging to probe tumor vascular properties. Compressed sensing (CS) theory makes it possible to recover MR images from randomly undersampled k-space data using nonlinear recovery schemes. The purpose of this paper is to quantitatively evaluate common temporal sparsity-promoting regularizers for CS DCE-MRI of the breast. Methods. We considered five ubiquitous temporal regularizers on 4.5x retrospectively undersampled Cartesian in vivo breast DCE-MRI data: Fourier transform (FT), Haar wavelet transform (WT), total variation (TV), second-order total generalized variation (TGVα2), and nuclear norm (NN). We measured the signal-to-error ratio (SER) of the reconstructed images, the error in tumor mean, and concordance correlation coefficients (CCCs) of the derived pharmacokinetic parameters Ktrans (volume transfer constant) and ve (extravascular-extracellular volume fraction) across a population of random sampling schemes. Results. NN produced the lowest image error (SER: 29.1), while TV/TGVα2 produced the most accurate Ktrans (CCC: 0.974/0.974) and ve (CCC: 0.916/0.917). WT produced the highest image error (SER: 21.8), while FT produced the least accurate Ktrans (CCC: 0.842) and ve (CCC: 0.799). Conclusion. TV/TGVα2 should be used as temporal constraints for CS DCE-MRI of the breast.
Year
DOI
Venue
2017
10.1155/2017/7835749
Periodicals
Field
DocType
Volume
Computer vision,Population,Contrast-enhanced Magnetic Resonance Imaging,Pattern recognition,Computer science,Matrix norm,Fourier transform,Correlation,Artificial intelligence,Haar wavelet,Dynamic contrast-enhanced MRI,Compressed sensing
Journal
2017
Issue
ISSN
Citations 
1
1687-4188
0
PageRank 
References 
Authors
0.34
6
5
Name
Order
Citations
PageRank
Dong Wang1214.12
Lori R. Arlinghaus2113.35
Thomas E. Yankeelov3207.14
Xiaoping Yang4115.00
David S. Smith5505.85