Title
Altering indispensable proteins in controlling directed human protein interaction network.
Abstract
The numerous interconnections within complex systems enable us to control networks towards a desired state through a few suitable selected nodes, which are called driver nodes. Recent works analyzed directed human Protein-Protein Interaction (PPI) network based on structural control theory. They found that indispensable proteins, whose removal increase the number of driver nodes, are the primary t...
Year
DOI
Venue
2018
10.1109/TCBB.2018.2796572
IEEE/ACM Transactions on Computational Biology and Bioinformatics
Keywords
Field
DocType
Proteins,Stability analysis,Diseases,Control theory,Drugs,Controllability
Complex system,Protein Interaction Map,Controllability,Computer science,Interaction network,Artificial intelligence,Computational biology,Machine learning
Journal
Volume
Issue
ISSN
15
6
1545-5963
Citations 
PageRank 
References 
0
0.34
0
Authors
1
Name
Order
Citations
PageRank
Xi-zhe Zhang1388.94