Title
Learning-based approach to segment pigment signs in fundus images for Retinitis Pigmentosa analysis.
Abstract
The automatic segmentation of variations in fundus images is being increasingly developed to establish retinal health, and to diagnose and monitor retinal abnormality. Fundus images can be acquired by low-cost and easy access diagnostic systems also in resource limited countries. In this paper, we focus on the segmentation of pigment signs in retinal fundus images, which is an important step in the diagnosis and monitoring of Retinitis Pigmentosa. At present, most of the existing approaches adopted for this purpose are based on the analysis of Optical Coherence Tomography (OCT) data, with only a few algorithms working on fundus images. The contribution of this paper is twofold. First, we propose a supervised segmentation technique for pigment sign detection in fundus images, which exploits the ensemble classifiers for both bagged and boosted decision trees, namely Random Forests and AdaBoost.M1. The ensemble classifiers are trained on feature vectors encoding the information of a set of regions obtained by partitioning a pre-processed image, so that each region is labeled as either normal fundus or pigment sign. Secondly, we have collected a large dataset of retinal images, in which the pigment signs have been segmented manually and we are making this publicly available to the research community. The performance of the classifiers has been evaluated on the proposed dataset and can be considered as a baseline for comparison. Our results demonstrate the high effectiveness of a machine learning approach as a suitable tool for automated Retinitis Pigmentosa analysis.
Year
DOI
Venue
2018
10.1016/j.neucom.2018.04.065
Neurocomputing
Keywords
Field
DocType
Retinitis Pigmentosa,Pigment signs,Medical image analysis,Ensemble classification,Segmentation
Retinitis pigmentosa,Optical coherence tomography,Feature vector,Pattern recognition,Segmentation,Fundus (eye),Artificial intelligence,Random forest,Alternating decision tree,Mathematics,Encoding (memory)
Journal
Volume
ISSN
Citations 
308
0925-2312
0
PageRank 
References 
Authors
0.34
17
7
Name
Order
Citations
PageRank
Nadia Brancati1297.76
Maria Frucci219026.24
Diego Gragnaniello316212.51
Daniel Riccio417023.60
Valentina Di Iorio510.70
Luigi Di Perna611.04
Francesca Simonelli701.01