Title
Differential Expression Analysis of RNA-seq Reads: Overview, Taxonomy and Tools.
Abstract
Analysis of RNA-sequence (RNA-seq) data is widely used in transcriptomic studies and it has many applications. We review RNA-seq data analysis from RNA-seq reads to the results of differential expression analysis. In addition, we perform a descriptive comparison of tools used in each step of RNA-seq data analysis along with a discussion of important characteristics of these tools. A taxonomy of tools is also provided. A discussion of issues in quality control and visualization of RNA-seq data is also included along with useful tools. Finally, we provide some guidelines for the RNA-seq data analyst, along with research issues and challenges which should be addressed.
Year
DOI
Venue
2020
10.1109/TCBB.2018.2873010
IEEE/ACM transactions on computational biology and bioinformatics
Keywords
DocType
Volume
Tools,Data analysis,Bioinformatics,Quality control,RNA,Sequential analysis,Gene expression
Journal
17
Issue
ISSN
Citations 
2
1545-5963
1
PageRank 
References 
Authors
0.36
0
3
Name
Order
Citations
PageRank
Hussain Ahmed Chowdhury110.70
Dhruba Kumar Bhattacharyya2506.95
Jugal K. Kalita385662.32