Title
A MapReduce Based Tool for the Analysis and Discovery of Novel Therapeutic Targets
Abstract
We present here a novel algorithm based on a MapReduce approach to facilitate the discovery of novel therapeutic targets. The proposed algorithm has been enabled to scan a set biological pathways in order to discover non-trivial (less common) routes. Such routes represent a chain of biochemical interactions among different biological actors. These actors can be represented by quite distant nodes along the devised pathway. Our approach detects nodes that are far from the initial target nodes, also showing the number of times that a given route has been found inside the selected set of biological pathways.
Year
DOI
Venue
2019
10.1109/EMPDP.2019.8671609
2019 27th Euromicro International Conference on Parallel, Distributed and Network-Based Processing (PDP)
Keywords
Field
DocType
Graphical user interfaces,Proteins,Libraries,Software algorithms,Software,Tools
Computer science,Graphical user interface,Software,Distributed computing
Conference
ISSN
ISBN
Citations 
1066-6192
978-1-7281-1644-0
0
PageRank 
References 
Authors
0.34
0
7
Name
Order
Citations
PageRank
Giuseppe Parasiliti100.68
Marzio Pennisi210923.03
Pietro Biondi342.62
Giuseppe Sgroi421.83
Giulia Russo561.06
Christian Napoli620124.64
Francesco Pappalardo718928.53