Title
Predicting temporal propagation of seasonal influenza using improved gaussian process model
Abstract
Influenza rapidly spreads in seasonal epidemics and imposes a considerable economic burden on hospitals and other healthcare costs. Thus, predicting the propagation of influenza accurately is crucial in preventing influenza outbreaks and protecting public health. Most current studies focus on the spread simulation of influenza. However, few studies have investigated the dependencies between meteorological variables and influenza activity. This study develops a non-parametric model based on Gaussian process regression for influenza prediction considering meteorological effect to capture temporal dependencies hidden in influenza time series. To identify the most explanatory external variables, L 1 -regularization is applied to identify meteorology factor subsets, and three types of covariance functions are designed to characterize non-stationary and periodic behavior in influenza activity. The dependencies of diseases and meteorology are modeled through the designed cross-covariance function. A real case in Shenzhen, China was studied to validate our proposed model along with comparisons to recently developed multivariate statistical models for influenza prediction. Results show that our proposed influenza prediction approach achieves superior performance in terms of one-week-ahead prediction of influenza-like illness. © 2019 Elsevier Inc.
Year
DOI
Venue
2019
10.1016/j.jbi.2019.103144
Journal of Biomedical Informatics
Keywords
Field
DocType
Gaussian process regression,Regularization,Seasonal influenza,Temporal propagation
Econometrics,Kriging,Data mining,Computer science,Multivariate statistics,External variable,Gaussian process,Statistical model,Covariance
Journal
Volume
Citations 
PageRank 
93
1
0.35
References 
Authors
0
13
Name
Order
Citations
PageRank
Shanen Chen121.36
Jian Xu2265.23
Yongsheng Wu322.38
Xin Wang43315.75
Shisong Fang510.68
Jinquan Cheng611.02
Hanwu Ma730.74
Renli Zhang810.68
Yachuan Liu910.35
Li Zhang102286151.94
Xi Zhang1110.35
Lili Chen1231.73
Xiaojian Liu1310.68