Title
Validation of an automatic algorithm to identify NeuroPace depth leads in CT images.
Abstract
Responsive neurostimulation (RNS) is a novel surgical intervention for treating medically refractory epilepsy. A neurostimulator implanted under the skull monitors brain activity in one or two seizure foci and provides direct electrical stimulation using implanted electrodes to prevent partial onset seizures. Despite significant successes in reducing seizure frequency over time, outcomes are less than optimal in a number of patients. To maximize treatment efficacy, it is critical to identify the factors that contribute to the variance in outcomes, including accurate knowledge of the final electrode location. However, there is as yet no automated algorithm to localize the RNS electrodes in the brain. Currently, physicians manually demarcate the positions of the leads in postoperative images, a method that is affected by rater bias and is impractical for largescale studies. In this paper, we propose an intensity feature based algorithm that can automatically identify the electrode positions in postoperative CT images. We also validate the performance of our algorithm on a multicenter dataset of 13 implanted patients and test how it compares with expert raters.
Year
DOI
Venue
2019
10.1117/12.2512580
Proceedings of SPIE
Keywords
Field
DocType
Refractory Epilepsy,RNS,Neuropace
Pattern recognition,Computer science,Artificial intelligence
Conference
Volume
ISSN
Citations 
10951
0277-786X
0
PageRank 
References 
Authors
0.34
0
9
Name
Order
Citations
PageRank
Srijata Chakravorti112.39
Rui Li231119.49
W Rodriguez300.68
Robert Shults400.34
Ashwini Sharan5213.32
Dario J. Englot600.68
Peter E. Konrad77812.43
Pierre-françois D'haese8437.54
Benoit M. Dawant91388223.11