Title
Automatic multi-modality segmentation of gross tumor volume for head and neck cancer radiotherapy using 3D U-Net.
Abstract
Accurate delineation of gross tumor volume (GTV) is essential for head and neck cancer radiotherapy. Complexity of morphology and potential image artifacts usually cause inaccurate manual delineation and interobserver variability. Manual delineation is also time consuming. Motivated by the recent success of deep learning methods in natural and medical image processing, we propose an automatic GTV segmentation approach based on 3D-Unet to achieve automatic GTV delineation. One innovative feature of our proposed method is that PET/CT multi-modality images are integrated in the segmentation network. 175 patients are included in this study with manually drawn GTV by physicians. Based on results from 5-fold cross validation, our proposed method achieves a dice loss of 0.82 +/- 0.07 which is better than the model using PET image only (0.79 +/- 0.09). In conclusion, automatic GTV segmentation is successfully applied to head and neck cancer patients using deep learning network and multi-modality images, which brings unique benefits for radiation therapy planning.
Year
DOI
Venue
2019
10.1117/12.2513229
Proceedings of SPIE
Keywords
Field
DocType
Head and Neck Cancer,Gross Tumor Volume,Deep Learning,Segmentation
Segmentation,Radiation therapy,Radiology,Gross tumor volume,Head and neck cancer,Medicine
Conference
Volume
ISSN
Citations 
10950
0277-786X
0
PageRank 
References 
Authors
0.34
0
4
Name
Order
Citations
PageRank
Zhe Guo121.76
Ning Guo2146.52
Kuang Gong3235.10
Quanzheng Li418132.36