Title | ||
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A homologous mapping method for three-dimensional reconstruction of protein networks reveals disease-associated mutations. |
Abstract | ||
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Our results demonstrate that hDiSNet can explore structural-based interactions insights for understanding the mechanisms of disease-associated proteins and their mutations. We believe that our method is useful to reconstruct structurally resolved PPI networks for interpreting structural genomics and disease associations. |
Year | DOI | Venue |
---|---|---|
2018 | 10.1186/s12918-018-0537-2 | BMC Systems Biology |
Keywords | Field | DocType |
Disease-associated proteins with mutations,Homologous mapping method,Structural systems biology,Structurally resolved PPI networks | ErbB Receptors,Disease,Interactome,Molecular interactions,Biology,Cell biology,Systems biology,Cell,Computational biology,Homologous chromosome,Mutation | Journal |
Volume | Issue | ISSN |
12 | 2 | 1752-0509 |
Citations | PageRank | References |
0 | 0.34 | 11 |
Authors | ||
5 |
Name | Order | Citations | PageRank |
---|---|---|---|
Sing-Han Huang | 1 | 1 | 1.75 |
Yu-Shu Lo | 2 | 40 | 4.57 |
Yong-Chun Luo | 3 | 0 | 0.34 |
Yu-Yao Tseng | 4 | 0 | 0.68 |
Jinn-moon Yang | 5 | 364 | 35.89 |