Title
A homologous mapping method for three-dimensional reconstruction of protein networks reveals disease-associated mutations.
Abstract
Our results demonstrate that hDiSNet can explore structural-based interactions insights for understanding the mechanisms of disease-associated proteins and their mutations. We believe that our method is useful to reconstruct structurally resolved PPI networks for interpreting structural genomics and disease associations.
Year
DOI
Venue
2018
10.1186/s12918-018-0537-2
BMC Systems Biology
Keywords
Field
DocType
Disease-associated proteins with mutations,Homologous mapping method,Structural systems biology,Structurally resolved PPI networks
ErbB Receptors,Disease,Interactome,Molecular interactions,Biology,Cell biology,Systems biology,Cell,Computational biology,Homologous chromosome,Mutation
Journal
Volume
Issue
ISSN
12
2
1752-0509
Citations 
PageRank 
References 
0
0.34
11
Authors
5
Name
Order
Citations
PageRank
Sing-Han Huang111.75
Yu-Shu Lo2404.57
Yong-Chun Luo300.34
Yu-Yao Tseng400.68
Jinn-moon Yang536435.89