Title | ||
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Exploitation of reverse vaccinology and immunoinformatics as promising platform for genome-wide screening of new effective vaccine candidates against <Emphasis Type="Italic">Plasmodium falciparum</Emphasis> |
Abstract | ||
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The present study systematically screened 5 potential protective antigens from P. falciparum genome using bioinformatics tools. Interestingly, these GDPAA, RSKMA and EKE of P. falciparum epitope ensembles forecasted to contain highly promiscuous T cell epitopes, which are potentially effective for most of the world-wide human population with malaria endemic regions. Therefore, these epitope ensembles could be considered in near future for novel and significantly effective vaccine candidate against malaria. |
Year | DOI | Venue |
---|---|---|
2019 | 10.1186/s12859-018-2482-x | BMC Bioinformatics |
Keywords | Field | DocType |
Malaria, Antigen, Epitopes, Population coverage, Vaccine, Plasmodium falciparum | Genome,Epitope,Population,Reverse vaccinology,Biology,MHC class I,Malaria vaccine,Plasmodium falciparum,Malaria,Genetics | Journal |
Volume | Issue | ISSN |
19 | 13 | 1471-2105 |
Citations | PageRank | References |
0 | 0.34 | 4 |
Authors | ||
5 |
Name | Order | Citations | PageRank |
---|---|---|---|
Manisha Pritam | 1 | 0 | 0.34 |
Garima Singh | 2 | 0 | 0.68 |
Suchit Swaroop | 3 | 0 | 0.34 |
Akhilesh Kumar Singh | 4 | 0 | 0.34 |
Satarudra Prakash Singh | 5 | 0 | 0.68 |