Title
Three dimensional structure prediction of panomycocin, a novel Exo-β-1,3-glucanase isolated from Wickerhamomyces anomalus NCYC 434 and the computational site-directed mutagenesis studies to enhance its thermal stability for therapeutic applications.
Abstract
•Reliable 3D structure of panomycocin was generated with homology modeling.•Computational site-directed mutagenesis was carried out to detect positions that would enhance the thermal stability.•Three positions outside and a position inside the binding region were detected to enhance the thermal stability.
Year
DOI
Venue
2019
10.1016/j.compbiolchem.2019.04.006
Computational Biology and Chemistry
Keywords
DocType
Volume
Antifungal protein,Panomycocin,Exo-β-1, 3-glucanase,Homology modeling,Computational site-directed mutagenesis,Thermal stability
Journal
80
ISSN
Citations 
PageRank 
1476-9271
0
0.34
References 
Authors
0
3
Name
Order
Citations
PageRank
Muhammed Tilahun Muhammed100.34
Çağdaş Devrim Son200.34
Fatih İzgü300.34