Title
Weakly-Supervised Simultaneous Evidence Identification and Segmentation for Automated Glaucoma Diagnosis
Abstract
Evidence identification, optic disc segmentation and automated glaucoma diagnosis are the most clinically significant tasks for clinicians to assess fundus images. However, delivering the three tasks simultaneously is extremely challenging due to the high variability of fundus structure and lack of datasets with complete annotations. In this paper, we propose an innovative Weakly-Supervised Multi-Task Learning method (WSMTL) for accurate evidence identification, optic disc segmentation and automated glaucoma diagnosis. The WSMTL method only uses weak-label data with binary diagnostic labels (normal/glaucoma) for training, while obtains pixel-level segmentation mask and diagnosis for testing. The WSMTL is constituted by a skip and densely connected CNN to capture multi-scale discriminative representation of fundus structure; a well-designed pyramid integration structure to generate high-resolution evidence map for evidence identification, in which the pixels with higher value represent higher confidence to highlight the abnormalities; a constrained clustering branch for optic disc segmentation; and a fully-connected discriminator for automated glaucoma diagnosis. Experimental results show that our proposed WSMTL effectively and simultaneously delivers evidence identification, optic disc segmentation (89.6% TP Dice), and accurate glaucoma diagnosis (92.4% AUC). This endows our WSMTL a great potential for the effective clinical assessment of glaucoma.
Year
Venue
Field
2019
THIRTY-THIRD AAAI CONFERENCE ON ARTIFICIAL INTELLIGENCE / THIRTY-FIRST INNOVATIVE APPLICATIONS OF ARTIFICIAL INTELLIGENCE CONFERENCE / NINTH AAAI SYMPOSIUM ON EDUCATIONAL ADVANCES IN ARTIFICIAL INTELLIGENCE
Glaucoma,Discriminator,Pattern recognition,Computer science,Segmentation,Fundus (eye),Optic disc,Constrained clustering,Artificial intelligence,Pixel,Discriminative model,Machine learning
DocType
Citations 
PageRank 
Conference
1
0.34
References 
Authors
0
5
Name
Order
Citations
PageRank
Rongchang Zhao193.81
Wangmin Liao210.34
Beiji Zou323141.61
Zailiang Chen4439.10
Shuo Li588772.47