Title
Blood-To-Blood Immunological Compatibility Test: A Possibility With Fluorescent Immuno-Biochips
Abstract
One of the most feared transfusion accident is the haemolytic reaction. A majority of countries imposes a compatibility test before each transfusion, at the patient's bedside or in laboratory. Regardless of the test performed, it does not prevent human errors and nothing ensures an "error free" procedure. Complete crossmatch is the only test ensuring a complete blood compatibility between donors and patients. It relies on the direct or indirect detection of agglutinations which occur when the patient's plasma is mixed with the red cells to be transfused. It requires extracting plasma. The work described here will help avoid all the immunologic incompatibilities by the use of a compatibility test without plasma extraction. It relies on an immuno-biochip technology in a microfluidic environment with fluorescence detection. This position paper presents preliminary results obtained with artificial samples together with comments on the state of industrial competition and the new device market positioning.
Year
DOI
Venue
2019
10.5220/0007356001600166
PROCEEDINGS OF THE 12TH INTERNATIONAL JOINT CONFERENCE ON BIOMEDICAL ENGINEERING SYSTEMS AND TECHNOLOGIES, VOL 1 (BIODEVICES)
Keywords
Field
DocType
Crossmatch, Human Red Blood Cells, Fluorescence, Biochip, Immuno-detection
Biomedical engineering,Biochip,Compatibility (mechanics),Computer science,Fluorescence,Artificial intelligence,Machine learning
Conference
Citations 
PageRank 
References 
0
0.34
0
Authors
8
Name
Order
Citations
PageRank
Karine Charrière111.98
A. Guitton200.34
V. Ratié300.34
L. Sighi-Dumoulin400.34
V. Bourcier500.34
Pascal Morel672.56
Lionel Pazart715.02
Bruno Wacogne815.36