Title
Fast and High-resolution Three-dimensional Hybrid-domain Photoacoustic Imaging Incorporating Analytical Focused Transducer Beam Amplitude.
Abstract
Recently, many reconstruction methods have been developed to improve the lateral resolution of acoustic-resolution photoacoustic microscopy (ARPAM) in out-of-focus regions. Though these methods enhance image resolution to some extent, they require advanced computational hardware and large computational time, especially for three-dimensional (3-D) cases. However, some methods do not consider the finite size of a transducer, while others employ numerical discretization to build a focused transducer model that is less efficient and accurate. To overcome these problems, we propose a 3-D ARPAM imaging reconstruction method with high precision, high efficiency, and low memory cost. It inherits the framework of model-based reconstructions and incorporates the forward acoustic model in the hybrid domain. This hybrid-domain acoustic model promotes an analytical solution to establish a focused transducer model. Furthermore, the non-uniform fast Fourier transform (NUFFT) and deconvolution methods are introduced to reduce the required computational time and memory volume for 3-D reconstructions. According to the experimental results reconstructed by the proposed method, the lateral resolution of an ARPAM image recorded by a 20-MHz focused transducer (NA 0.393) can reach 88.39 <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\mu \text{m}$ </tex-math></inline-formula> . This resolution exceeds the diffraction limitation of the focused transducer ( <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$137.8~\mu \text{m}$ </tex-math></inline-formula> ). When reconstructing a 3-D image with <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${200}\times {200}\times {150}$ </tex-math></inline-formula> pixels, the proposed method takes only 8.15 s using a laptop loaded with Intel Core i7-8550U CPU at 1.8 GHz and 1.06-GB memory.
Year
DOI
Venue
2019
10.1109/TMI.2019.2917688
IEEE transactions on medical imaging
Keywords
Field
DocType
Transducers,Image reconstruction,Mathematical model,Acoustics,Imaging,Detectors,Image resolution
Transducer,Computer vision,Photoacoustic imaging in biomedicine,Optics,Artificial intelligence,Beam (structure),Amplitude,Mathematics
Journal
Volume
Issue
ISSN
38
12
0278-0062
Citations 
PageRank 
References 
1
0.39
0
Authors
4
Name
Order
Citations
PageRank
Haoran Jin133.86
Ruochong Zhang213.77
Siyu Liu3188.31
Yuanjin Zheng432872.86