Paper Info
Title
Repolarization variability independent of heart rate during sympathetic activation elicited by head-up tilt.
Abstract
The fraction of repolarization variability independent of RR interval variability is of clinical interest. It has been linked to direct autonomic nervous system (ANS) regulation of the ventricles in healthy subjects and seems to reflect the instability of the ventricular repolarization process in heart disease. In this study, we sought to identify repolarization measures that best reflect the sympathetic influences on the ventricles independent of the RR interval. ECG was recorded in 46 young subjects during supine and then following 45 degrees head-up tilt. RR intervals and five repolarization features (QTend, QTpeak, RTend, RTpeak, and TpTe) were extracted from the ECG recordings. Repolarization variability was separated into RR-dependent and RR-independent variability using parametric spectral analysis. Results show that LF power of TpTe is independent of RR in both supine and tilt, while the LF power of QTend and RTend independent of RR and respiration increases following tilt. We conclude that TpTe is independent of RR and is highly affected by respiration. QTend and RTend LF power might reflect the sympathetic influences on the ventricles elicited by tilt.
Year
DOI
Venue
2019
10.1007/s11517-019-01998-9
Medical & Biological Engineering & Computing
Keywords
Field
DocType
Repolarization, Heart rate variability, QT interval, Tpeak-Tend, Sympathetic activation, Head-up tilt, Autonomic nervous system
QT interval,Artificial intelligence,Heart rate,Supine position,Heart disease,Computer vision,Autonomic nervous system,Respiration,Internal medicine,Heart rate variability,Cardiology,Repolarization,Mathematics
Journal
Volume
Issue
ISSN
57
8
0140-0118
Citations 
PageRank 
References 
0
0.34
0
Authors
7
Name
Order
Citations
PageRank
Fatima El-Hamad100.34
Michal Javorka23910.94
Barbora Czippelova385.63
Jana Krohova4134.45
Zuzana Turianikova5115.82
Alberto Porta6176.53
Mathias Baumert73611.50