Name
Abstract | ||
|---|---|---|
The identification of protein complexes is becoming increasingly important to our understanding of cellular functionality. However, if a biologist wishes to investigate a certain protein, currently no method exists to assist him/her to accurately retrieve the possible protein partners that are expected to be in the same functional complex. Here, we introduce ProtRet, a web server that functions as an interface for an improved Pigeonhole approach to identify protein complexes in protein-protein interaction networks. The approach provides high-quality protein comparison that is particularly valuable because of its accurate statistical estimates based on fuzzy criterion and Hamming distance. The proposed method was tested on two high-throughput experimental protein-protein interaction data sets and two gold standard data sets and was able to retrieve more correct protein members than all existing methods. |
Year | DOI | Venue |
|---|---|---|
2019 | 10.1007/978-3-030-23873-5_1 | PRACTICAL APPLICATIONS OF COMPUTATIONAL BIOLOGY AND BIOINFORMATICS |
Keywords | DocType | Volume |
Protein complexes,Protein-protein interaction,Pigeonhole method,Information retrieval | Conference | 1005 |
ISSN | Citations | PageRank |
2194-5357 | 0 | 0.34 |
References | Authors | |
0 | 3 | |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Nazar Zaki | 1 | 139 | 14.31 |
| Maryam Al Yammahi | 2 | 0 | 0.34 |
| Tetiana Habuza | 3 | 0 | 0.34 |