Paper Info
Title
Comparing Subjects with Reference Populations - A Visualization Toolkit for the Analysis of Aortic Anatomy and Pressure Distribution.
Abstract
The analysis of anatomical and hemodynamic vessel parameters plays an important role in diagnosis and therapy planning for aortic diseases. Normal values and decision thresholds are usually based on global or local parameters provided by population studies. In order to enable a more holistic comparison of a single subject and a matching reference population we have developed a spatiotemporal normalization concept for the analysis of 4D PC MRI data of the thoracic aorta. This enables the comparison of geometric properties and pressure differences along the vessel course as well as in a sector model, which represents a cross-sectional value distribution. We tested the applicability of the presented approach by comparing subjects with aortic diseases to matching subgroups of a normal reference population. The presented framework enabled a visual and quantitative assessment of the local geometric and pressure distribution changes of different pathological alterations of the aorta. It will be extended to integrate further hemodynamic properties and larger reference cohorts to support clinical decision making based on hemodynamic information in near future.
Year
DOI
Venue
2019
10.1007/978-3-030-21949-9_40
Lecture Notes in Computer Science
Keywords
Field
DocType
4D PC MRI,Aortic disease,Pressure distribution,Population study
Hemodynamics,Population,Normalization (statistics),Visualization,Internal medicine,Cardiology,Thoracic aorta,Quantitative assessment,Therapy planning,Medicine,Aorta
Conference
Volume
ISSN
Citations 
11504
0302-9743
0
PageRank 
References 
Authors
0.34
0
6
Name
Order
Citations
PageRank
Sahar Karimkeshteh100.34
Lilli Kaufhold200.68
Sarah Nordmeyer310.70
Lina Jarmatz400.34
Andreas Harloff5134.06
Anja Hennemuth615925.15