Paper Info
Title
Effect of Prenatal Organic Solvent Exposure on Structural Connectivity at Childhood
Abstract
Glycol ethers are part of organic solvents. They are used in industry and at home during manufacturing or usage of products such as paints, cleaning agents and cosmetics. The specific detection of subtle, low-dose effects of early-life exposure to these solvents on neuropsychological performance in children is a trendy subject of investigation. Neuroimaging allows looking into brain function and identifying different cerebral connections that may be affected by these neurotoxicants. In this paper, we investigated the specific effects of prenatal low-level exposure to different glycol ethers, on brain development of children between 10 and 12 years old. Based on previous studies suggesting cognitive disabilities in the attention, inhibition and working memory, we proposed a structural connectivity analysis using graph theory restricted to the regions involved in these functions. Our results suggest a possible relationship between the attention, working memory and inhibition and prenatal exposure to specific glycol ethers, such as ethoxyacetic acid, ethoxyethoxyacetic acid and 2-butoxyacetic acid.
Year
DOI
Venue
2019
10.1109/ISBI.2019.8759473
2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019)
Keywords
Field
DocType
diffusion-weighted imaging,graph theory,diffusion,organic solvents,brain development
Brain development,Neuroscience,Pattern recognition,Computer science,Working memory,Glycol ethers,Cognitive disabilities,Artificial intelligence,Ethoxyacetic acid,Solvent exposure,Neuropsychology
Conference
ISSN
ISBN
Citations 
1945-7928
978-1-5386-3642-8
0
PageRank 
References 
Authors
0.34
0
7
Name
Order
Citations
PageRank
Julie Coloigner100.34
Anne-Claire Binter200.34
Elise Bannier3163.99
Jean-Christophe Ferré4186.07
Cécile Chevrier500.68
Christian Barillot61290133.50
Fabienne Pelé700.34