Title
Quantifying the Intra-Operative Hemodynamic Effects of Glue Embolization in Vein of Galen Malformations.
Abstract
Vein of Galen malformation is a rare congenital pathological intracranial arteriovenous shunt which carries 30% risk of death before 28 days-of-age. Treatment is by high risk minimally invasive endovascular glue embolization of shunt feeding arteries under angiographic control. A tool to support intra-operative decision making would be useful. We present a novel method for visualizing angiography data to demonstrate the effect of the intervention based upon change the after embolization in the delay in time of peak contrast density relative to the injected artery and a novel method for quantifying the immediate effect of embolization on the hemodynamics of the shunt. The method is demonstrated on the angiograms of five neonates who underwent embolization. We show consistent results including a post-embolization increase in the delay in time of peak contrast density relative to the injected artery at the venous outflow in keeping with reduced shunting and redistribution of blood following embolization.
Year
DOI
Venue
2019
10.1109/ISBI.2019.8759485
ISBI
Keywords
Field
DocType
Vein of Galen malformation,embolization,quantitative angiography,vessel flow
Hemodynamics,Artery,Computer vision,Shunting,Shunt (electrical),Vein,Artificial intelligence,Embolization,Radiology,GLUE,Medicine,Angiography
Conference
Volume
ISSN
Citations 
2019
1945-7928
0
PageRank 
References 
Authors
0.34
0
10
Name
Order
Citations
PageRank
Premal A. Patel100.34
Dimitra Flouri200.34
Adam Rennie300.34
Fergus Robertson400.34
Lauren Davies500.34
Vijeya Ganesan600.34
Sanjay Bhate700.34
Paolo De Coppi8101.56
Tom Vercauteren91956108.68
Andrew Melbourne1013618.05