Name
Title | ||
|---|---|---|
Simulations of the effect of diffusion on asymmetric spin echo based quantitative BOLD: An investigation of the origin of deoxygenated blood volume overestimation. |
Abstract | ||
|---|---|---|
Quantitative BOLD (qBOLD) is a technique for mapping oxygen extraction fraction (OEF) and deoxygenated blood volume (DBV) in the human brain. Recent measurements using an asymmetric spin echo (ASE) based qBOLD approach produced estimates of DBV which were systematically higher than measurements from other techniques. In this study, we investigate two hypotheses for the origin of this DBV overestimation using simulations and consider the implications for experimental measurements. Investigations were performed by combining Monte Carlo simulations of extravascular signal with an analytical model of the intravascular signal. |
Year | DOI | Venue |
|---|---|---|
2019 | 10.1016/j.neuroimage.2019.116035 | NeuroImage |
Keywords | Field | DocType |
Quantitative BOLD,Magnetic resonance imaging,Monte Carlo simulation,Oxygen extraction fraction,Cerebral blood volume | Monte Carlo method,Computational physics,Cognitive psychology,Psychology,Oxygen extraction,Radius,Spin echo,Venous blood | Journal |
Volume | ISSN | Citations |
201 | 1053-8119 | 1 |
PageRank | References | Authors |
0.36 | 0 | 4 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Alan J. Stone | 1 | 46 | 3.41 |
| Naomi C Holland | 2 | 1 | 0.36 |
| Avery J L Berman | 3 | 1 | 0.36 |
| Nicholas Blockley | 4 | 99 | 8.41 |