Title
Phenotyping UK Electronic Health Records from 15 Million Individuals for Precision Medicine: The CALIBER Resource.
Abstract
Electronic health records (EHR) are increasingly being used for observational research at scale. In the UK, we have established the CALIBER research resource which utilizes national primary and hospital EHR data sources and enables researchers to create and validate longitudinal disease phenotypes at scale. In this work, we will describe the core components of the resource and provide results from three exemplar research studies on high-resolution epidemiology, disease risk prediction and subtype discovery which demonstrate both the opportunities and challenges of using EHR for research.
Year
DOI
Venue
2019
10.3233/SHTI190058
Studies in Health Technology and Informatics
Keywords
Field
DocType
electronic health records,phenotyping,data linkage,prognosis,biomedical informatics
Precision medicine,Caliber,Medical physics,Medicine
Conference
Volume
ISSN
Citations 
262
0926-9630
0
PageRank 
References 
Authors
0.34
0
5
Name
Order
Citations
PageRank
Spiros Denaxas112.65
Arturo Gonzalez-Izquierdo212.32
Natalie Fitzpatrick311.64
Kenan Direk410.96
Harry Hemingway5195.72