Title
A Sub-Pa Current Sensing Front-End For Transient Induced Molecular Spectroscopy
Abstract
We report an 8-channel array of low-noise (30.3fA/root Hz) current sensing front-ends with on-chip sensors for label-free, restriction-free biosensing. The analog front-end (AFE) consists of a 1st-order continuous-time delta-sigma (CT-Delta Sigma) modulator that achieves 123fA sensitivity and 139dB cross-scale dynamic range over a 10Hz bandwidth while consuming 50 mu W and occupying 0.11mm(2) per channel. A digital IIR filter and a tri-level pulse width modulated (PWM) current-steering DAC are used to realize the equivalent performance of a multi-bit Delta Sigma in an area/power efficient manner. This platform was used to observe protein-ligand interactions in real-time.
Year
DOI
Venue
2019
10.23919/VLSIC.2019.8777980
2019 SYMPOSIUM ON VLSI CIRCUITS
Field
DocType
Citations 
Front and back ends,System on a chip,Dynamic range,Computer science,Infinite impulse response,Pulse-width modulation,Communication channel,Electronic engineering,Modulation,Bandwidth (signal processing)
Conference
0
PageRank 
References 
Authors
0.34
0
5
Name
Order
Citations
PageRank
Da Ying100.34
Ping-Wei Chen200.34
Chi Tseng300.34
Yu-Hwa Lo411.37
Hall, D.A.511.98