Title | ||
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Mat_Peptide: Comprehensive annotation of mature peptides from polyproteins in five virus families. |
Abstract | ||
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Motivation: Sequence repositories have few well-annotated virus mature peptide sequences. Therefore post-translational proteolytic processing of polyproteins into mature peptides (MPs) has been performed in silico, with a new computational method, for over 200 species in 5 pathogenic virus families (Caliciviridae, Coronaviridae, Flaviviridae, Picornaviridae and Togaviridae). Results: Using pairwise alignment with reference sequences, MPs have been annotated and their sequences made available for search, analysis and download. At publication the method had produced 156 216 sequences, a large portion of the protein sequences now available in https://www.viprbrc.org. It represents a new and comprehensive mature peptide collection. |
Year | DOI | Venue |
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2020 | 10.1093/bioinformatics/btz777 | BIOINFORMATICS |
Field | DocType | Volume |
Annotation,Computer science,Polyproteins,Computational biology,Bioinformatics,Virus classification | Journal | 36 |
Issue | ISSN | Citations |
5 | 1367-4803 | 0 |
PageRank | References | Authors |
0.34 | 0 | 10 |
Name | Order | Citations | PageRank |
---|---|---|---|
Christopher N Larsen | 1 | 15 | 3.56 |
Guangyu Sun | 2 | 1 | 0.77 |
Xiaomei Li | 3 | 0 | 0.34 |
Sam Zaremba | 4 | 38 | 2.26 |
Hongtao Zhao | 5 | 0 | 0.34 |
Sherry He | 6 | 0 | 0.34 |
Liwei Zhou | 7 | 16 | 1.63 |
Sanjeev Kumar | 8 | 1 | 0.77 |
Vince Desborough | 9 | 0 | 0.34 |
Edward B Klem | 10 | 0 | 0.34 |