Title
Covariance Shrinkage for Dynamic Functional Connectivity.
Abstract
The tracking of dynamic functional connectivity (dFC) states in resting-state fMRI scans aims to reveal how the brain sequentially processes stimuli and thoughts. Despite the recent advances in statistical methods, estimating the high dimensional dFC states from a small number of available time points remains a challenge. This paper shows that the challenge is reduced by a statistical method used for the estimation of large covariance matrices from small number of samples. We present a computationally efficient formulation of our approach that scales dFC analysis up to full resolution resting-state fMRI scans. Experiments on synthetic data demonstrate that our approach produces dFC estimates that are closer to the ground-truth than state-of-the-art estimation approaches. When comparing methods on the rs-fMRI scans of 162 subjects, we found that our approach is better at extracting functional networks and capturing differences in rs-fMRI acquisition and diagnosis.
Year
DOI
Venue
2019
10.1007/978-3-030-32391-2_4
CNI@MICCAI
DocType
Volume
Citations 
Conference
11848
0
PageRank 
References 
Authors
0.34
0
6
Name
Order
Citations
PageRank
Nicolas Honnorat1316.92
Ehsan Adeli Mosabbeb226139.27
Qingyu Zhao324.09
Adolf Pfefferbaum417420.61
Edith V Sullivan515019.25
Kilian Pohl657746.78