Title | ||
---|---|---|
Feasibility of Using a 1T Extremity Scanner with a Four-Element Array to Detect 31P in the Human Calf. |
Abstract | ||
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The feasibility of conducting in vivo non-localized skeletal muscle P Magnetic Resonance Spectroscopy (MRS) with a low-cost extremity 1 Tesla magnet is demonstrated. We designed and built a transmit-only quadrature birdcage, four-element receive coil array, and employed a home-built spectrometer interfaced with a commercial ONI 1.0T magnet. In phantom comparison tests with a large loop coil of comparable size, the array was found to improve the SNR by a factor of 1.8 and the linewidth from 0.72 ppm to 0.45 ppm. Phantom and in vivo testing results show only 6 averages with a 4 second repetition time are required to obtain quantifiable P spectra. Initial in vivo human skeletal muscle P spectra successfully allowed for peak characterization. A low-cost approach to MRS could enable more widespread use of this tool in clinical diagnosis and in vivo metabolic research. |
Year | DOI | Venue |
---|---|---|
2019 | 10.1109/EMBC.2019.8857122 | EMBC |
DocType | Volume | ISSN |
Conference | 2019 | 1557-170X |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
4 |
Name | Order | Citations | PageRank |
---|---|---|---|
Travis Carrell | 1 | 0 | 0.34 |
Minyu Gu | 2 | 0 | 0.34 |
Mary P. McDougall | 3 | 0 | 0.34 |
Steven M Wright | 4 | 4 | 6.84 |