Title
Estimating the Dependence of Differential Pathlength Factor on Blood Volume and Oxygen Saturation using Monte Carlo method
Abstract
Differential Pathlength Factor (DPF) is a vital parameter for the Beer-Lambert law based calculations in estimating tissue perfusion using non-invasive optical techniques. A significant error in the measured concentration of oxyhemoglobin and deoxyhemoglobin has been reported due to the usage of wrong DPF values. The dependence of DPF on blood oxygen saturation and blood volume has never been studied earlier. In this work, a Monte Carlo model of perfused skin tissue was developed and executed at 660 nm and 940 nm optical wavelengths at a reflectance geometry. DPFs were simulated through 1-10 mm source detector separations at different blood volumes and oxygen saturations. Results showed higher DPFs at lower wavelengths and considerable variation with blood volume and oxygen saturation.
Year
DOI
Venue
2019
10.1109/EMBC.2019.8856437
2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Keywords
Field
DocType
Blood Volume,Monte Carlo Method,Oximetry,Oxygen,Oxyhemoglobins
Monte Carlo method,Analytical chemistry,Computer science,Oxygen saturation,Blood volume,Electronic engineering,Detector,Photonics,Wavelength,Light scattering,Perfusion
Conference
Volume
ISSN
ISBN
2019
1557-170X
978-1-5386-1312-2
Citations 
PageRank 
References 
0
0.34
2
Authors
2
Name
Order
Citations
PageRank
Subhasri Chatterjee100.34
P A Kyriacou22016.60