Title | ||
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Estimating the Dependence of Differential Pathlength Factor on Blood Volume and Oxygen Saturation using Monte Carlo method |
Abstract | ||
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Differential Pathlength Factor (DPF) is a vital parameter for the Beer-Lambert law based calculations in estimating tissue perfusion using non-invasive optical techniques. A significant error in the measured concentration of oxyhemoglobin and deoxyhemoglobin has been reported due to the usage of wrong DPF values. The dependence of DPF on blood oxygen saturation and blood volume has never been studied earlier. In this work, a Monte Carlo model of perfused skin tissue was developed and executed at 660 nm and 940 nm optical wavelengths at a reflectance geometry. DPFs were simulated through 1-10 mm source detector separations at different blood volumes and oxygen saturations. Results showed higher DPFs at lower wavelengths and considerable variation with blood volume and oxygen saturation. |
Year | DOI | Venue |
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2019 | 10.1109/EMBC.2019.8856437 | 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) |
Keywords | Field | DocType |
Blood Volume,Monte Carlo Method,Oximetry,Oxygen,Oxyhemoglobins | Monte Carlo method,Analytical chemistry,Computer science,Oxygen saturation,Blood volume,Electronic engineering,Detector,Photonics,Wavelength,Light scattering,Perfusion | Conference |
Volume | ISSN | ISBN |
2019 | 1557-170X | 978-1-5386-1312-2 |
Citations | PageRank | References |
0 | 0.34 | 2 |
Authors | ||
2 |
Name | Order | Citations | PageRank |
---|---|---|---|
Subhasri Chatterjee | 1 | 0 | 0.34 |
P A Kyriacou | 2 | 20 | 16.60 |