Name
Abstract | ||
|---|---|---|
High-gamma (H gamma) activity from electro-corticography (ECoG) is a common-used signal for understanding the human brain, but its interpretation is impeded by a lack of spatial localization. To address this, we developed a novel recording approach to simultaneously record mu ECoG cortical surface electrical potentials (CSEPs) and laminar multiunit activity (MUA). We demonstrate that stimulus evoked CSEPs carry a multi-modal frequency response, peaking in the H gamma range. Laminar MUA responses exhibited similar tuning to CSEP H gamma directly over the intracortical recording site, suggesting a functional relationship. We fit CSEP H gamma to the simultaneously-recorded laminar MUA using a state-of-the-art sparse multi-linear regression model to identify laminar contributions to cortical surface H gamma. Our results indicate that CSEP H gamma recorded by ECoG reflects spiking activity from neurons in layer 3. These results provide initial insight into localizing the sources of CSEPs, which will guide clinical and BMI device decisions. |
Year | DOI | Venue |
|---|---|---|
2019 | 10.1109/EMBC.2019.8856786 | 2019 41ST ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC) |
Field | DocType | Volume |
Computer vision,Neuroscience,Electrocorticography,Computer science,Laminar flow,Electrical potentials,Surface fitting,Spatial localization,Human brain,Artificial intelligence,Stimulus (physiology) | Conference | 2019 |
ISSN | Citations | PageRank |
1557-170X | 0 | 0.34 |
References | Authors | |
0 | 4 | |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Maximilian E. Dougherty | 1 | 0 | 0.34 |
| Anh P. Q. Nguyen | 2 | 0 | 0.34 |
| Vyassa L. Baratham | 3 | 0 | 0.34 |
| Kristofer E Bouchard | 4 | 18 | 8.99 |