Title
Perfusion Quantification Using Arterial Spin Labeling Magnetic Resonance Imaging After Revascularization For Moyamoya Disease
Abstract
The hemodynamics in the brains of individuals with Moyamoya disease are complex and variable. Cerebral revascularization is an important treatment when hemodynamics are severely damaged. It's of great value to accurately quantify blood perfusion of different functional brain regions for better postoperative prognosis. In this study, we developed methods to segment territory of middle cerebral arteries (MCA) and its functional brain regions based on T1 and arterial spin labeling (ASL) imaging, absolute and normalized cerebral blood perfusion (CBF) were calculated for target regions-of-interest (ROI), spatial coefficient of variation was introduced to detect information of arterial transit time (ATT) contained in CBF images. After revascularization of Moyamoya disease, we detected perfusion improvement within MCA territory, while different alterations exist within different functional sub-regions. We also conformed that the spatial coefficient of variation of ASL CBF images can be used as an alternative ROI-based hemodynamic measurement to predict alterations of ATT. In summary, our methods show potential in postoperative evaluation of patients with Moyamoya disease.
Year
DOI
Venue
2019
10.1109/EMBC.2019.8857824
2019 41ST ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)
Field
DocType
Volume
Computer science,Moyamoya disease,Site-directed spin labeling,Artificial intelligence,Cerebral Revascularization,Perfusion,Hemodynamics,Cerebral arteries,Computer vision,Internal medicine,Cardiology,Arterial Spin Labeling Magnetic Resonance Imaging,Revascularization
Conference
2019
ISSN
Citations 
PageRank 
1557-170X
0
0.34
References 
Authors
0
7
Name
Order
Citations
PageRank
Liang Li127714.18
Yu Lei200.34
JiaBin Su300.34
PengZheng Zhou400.68
Haiyan Lv501.01
Tong Wang632.41
Ting Ma701.69