Title
Out Of Distribution Detection For Intra-Operative Functional Imaging
Abstract
Multispectral optical imaging is becoming a key tool in the operating room. Recent research has shown that machine learning algorithms can be used to convert pixel-wise reflectance measurements to tissue parameters, such as oxygenation. However, the accuracy of these algorithms can only be guaranteed if the spectra acquired during surgery match the ones seen during training. It is therefore of great interest to detect so-called out of distribution (OoD) spectra to prevent the algorithm from presenting spurious results. In this paper we present an information theory based approach to OoD detection based on the widely applicable information criterion (WAIC). Our work builds upon recent methodology related to invertible neural networks (INN). Specifically, we make use of an ensemble of INNs as we need their tractable Jacobians in order to compute the WAIC. Comprehensive experiments with in silico, and in vivo multispectral imaging data indicate that our approach is well-suited for OoD detection. Our method could thus be an important step towards reliable functional imaging in the operating room.
Year
DOI
Venue
2019
10.1007/978-3-030-32689-0_8
UNCERTAINTY FOR SAFE UTILIZATION OF MACHINE LEARNING IN MEDICAL IMAGING AND CLINICAL IMAGE-BASED PROCEDURES
DocType
Volume
ISSN
Conference
11840
0302-9743
Citations 
PageRank 
References 
0
0.34
0
Authors
9
Name
Order
Citations
PageRank
Tim Adler113.08
Leonardo Ayala211.39
Lynton Ardizzone334.47
Hannes Kenngott400.34
Anant Suraj Vemuri5143.67
Beat P. Müller-Stich682.84
Carsten Rother79074451.62
Ullrich Koethe824922.37
Lena Maier-Hein962680.20