Title
Regularized Adversarial Training (RAT) for Robust Cellular Electron Cryo Tomograms Classification
Abstract
Cellular Electron Cryo Tomography (CECT) 3D imaging has permitted biomedical community to study macromolecule structures inside single cells with deep learning approaches. Many deep learning-based methods have since been developed to classify macromolecule structures from tomograms with high accuracy. However, several recent studies have demonstrated the lack of robustness in these models against often-imperceptible, designed changes of input. Therefore, making existing subtomogram-classification models robust remains a serious challenge. In this paper, we study the robustness of the state-of-the-art subtomogram classifier on CECT images and propose a method called Regularized Adversarial Training (RAT) to defend the classifier against a wide range of designed threats. Our results show that RAT improves robustness for CECT image classification over the previous methods.
Year
DOI
Venue
2019
10.1109/BIBM47256.2019.8982954
2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
Keywords
Field
DocType
Cellular Electron Cryo Tomography,Classification,Robustness,Adversarial Training,Adversarial Attacks
Computer science,Tomography,Robustness (computer science),Artificial intelligence,Deep learning,Classifier (linguistics),Contextual image classification,Machine learning
Conference
ISSN
ISBN
Citations 
2156-1125
978-1-7281-1868-0
0
PageRank 
References 
Authors
0.34
0
7