Title
Differential Diagnosis For Pancreatic Cysts In Ct Scans Using Densely-Connected Convolutional Networks
Abstract
The lethal nature of pancreatic ductal adenocarcinoma (PDAC) calls for early differential diagnosis of pancreatic cysts, which are identified in up to 16% of normal subjects, and some of them may develop into PDAC. Pancreatic cysts have a large variation in size and shape, and the precise segmentation of them remains rather challenging, which restricts the computer-aided interpretation of CT images acquired for differential diagnosis. We propose a computer-aided framework for early differential diagnosis of pancreatic cysts without pre-segmenting the lesions using densely-connected convolutional networks (Dense-Net). The Dense-Net learns high-level features from whole abnormal pancreas and builds mappings between medical imaging appearance to different pathological types of pancreatic cysts. To enhance the clinical applicability, we integrate saliency maps in the framework to assist the physicians to understand the decision of the deep learning method. The test on a cohort of 206 patients with 4 pathologically confirmed subtypes of pancreatic cysts has achieved an overall accuracy of 72.8%, which is significantly higher than the baseline accuracy of 48.1%. The superior performance on this challenging dataset strongly supports the clinical potential of our developed method.
Year
DOI
Venue
2019
10.1109/EMBC.2019.8856745
2019 41ST ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)
Field
DocType
Volume
Pancreatic cysts,Computer vision,Segmentation,Computer science,Medical imaging,Pathological,Artificial intelligence,Adenocarcinoma,Radiology,Cancer,Pancreas,Differential diagnosis
Conference
2019
ISSN
Citations 
PageRank 
1557-170X
0
0.34
References 
Authors
0
10
Name
Order
Citations
PageRank
Li Hongwei153561.38
Maximilian Reichert200.68
Kanru Lin300.34
Nikita Tselousov400.34
Rickmer Braren5433.10
Deliang Fu6111.35
roland m schmid721.48
Ji Li800.34
Bjoern H. Menze9103280.31
Kuangyu Shi10368.12