Title
Output feedback stabilizer design of Boolean networks based on network structure
Abstract
In genetic regulatory networks, a stable configuration can represent the evolutionary behavior of cell death or unregulated growth in genes. We present analytical investigations on output feedback stabilizer design of Boolean networks (BNs) to achieve global stabilization via the semi-tensor product method. Based on network structure information describing coupling connections among nodes, an output feedback stabilizer is designed to achieve global stabilization. Compared with the traditional pinning control design, the output feedback stabilizer design is not based on the state transition matrix of BNs, which can efficiently determine pinning control nodes and reduce computational complexity. Our proposed method is efficient in that the calculation of the state transition matrix with dimension 2n × 2n is avoided; here n is the number of nodes in a BN. Finally, a signal transduction network and a D. melanogaster segmentation polarity gene network are presented to show the efficiency of the proposed method. Results are shown to be simple and concise, compared with traditional pinning control for BNs.
Year
DOI
Venue
2020
10.1631/FITEE.1900229
Frontiers of Information Technology & Electronic Engineering
Keywords
DocType
Volume
Boolean networks, Output feedback stabilizer, Network structure, Semi-tensor product of matrices, TP183
Journal
21
Issue
ISSN
Citations 
2
2095-9184
6
PageRank 
References 
Authors
0.45
0
4
Name
Order
Citations
PageRank
Jie Zhong117114.53
Bowen Li212817.14
Yang Liu3859.62
Weihua Gui457790.82