Title
An Adversarial Learning Approach to Medical Image Synthesis for Lesion Detection
Abstract
The identification of lesion within medical image data is necessary for diagnosis, treatment and prognosis. Segmentation and classification approaches are mainly based on supervised learning with well-paired image-level or voxel-level labels. However, labeling the lesion in medical images is laborious requiring highly specialized knowledge. We propose a medical image synthesis model named abnormal-to-normal translation generative adversarial network (ANT-GAN) to generate a normal-looking medical image based on its abnormal-looking counterpart without the need for paired training data. Unlike typical GANs, whose aim is to generate realistic samples with variations, our more restrictive model aims at producing a normal-looking image corresponding to one containing lesions, and thus requires a special design. Being able to provide a “normal” counterpart to a medical image can provide useful side information for medical imaging tasks like lesion segmentation or classification validated by our experiments. In the other aspect, the ANT-GAN model is also capable of producing highly realistic lesion-containing image corresponding to the healthy one, which shows the potential in data augmentation verified in our experiments.
Year
DOI
Venue
2020
10.1109/JBHI.2020.2964016
IEEE Journal of Biomedical and Health Informatics
Keywords
DocType
Volume
Brain,Humans,Image Interpretation, Computer-Assisted,Unsupervised Machine Learning
Journal
24
Issue
ISSN
Citations 
8
2168-2194
4
PageRank 
References 
Authors
0.41
0
6
Name
Order
Citations
PageRank
Liyan Sun1112.22
Jiexiang Wang291.48
Yue Huang3356.24
Xinghao Ding459152.95
Hayit Greenspan52645319.45
John Paisley6544.63