Title
Impact of Metabolomics on Depression using Data Mining Techniques
Abstract
Depression is one of the most common mental disorders worldwide. Individual clinical interviews are typically the “gold standard” when diagnosing depressive disorders. However, these approaches are based on subjective evaluation and have many limitations. In our study, the impact of metabolomics approach on the assessment of depression is evaluated. The data mining techniques classification by fuzzy decision trees were used. We selected three profiles of metabolites from the groups of acylcarnitines, phosphatidylcholines and sphingomyelins. From these groups, the most accurate metabolites were selected using fuzzy decision tree to classify depression state. Our results clearly show that there are many metabolites that are influenced by depression when comparing with control rats. The results were verified by means and p-values. The benefit of the work is in applying a fuzzy decision tree to classify metabolites, specific for depression disorders, which could be used in clinical practice in the future.
Year
DOI
Venue
2019
10.1109/IDAACS.2019.8924245
2019 10th IEEE International Conference on Intelligent Data Acquisition and Advanced Computing Systems: Technology and Applications (IDAACS)
Keywords
Field
DocType
Depression,Data mining,Fuzzy decision trees,fuzzy clustering,acylcarnitines,phosphatidylcholines,sphingomyelins
Data mining,Fuzzy clustering,Computer science,Clinical Practice,Metabolomics,Artificial intelligence,Gold standard,Fuzzy decision tree,Machine learning
Conference
Volume
ISBN
Citations 
2
978-1-7281-4070-4
0
PageRank 
References 
Authors
0.34
0
6
Name
Order
Citations
PageRank
Olga Chovancova101.01
Andrea Stafurikova200.68
Denisa Macekova301.01
Terezia Kiskova400.68
Jan Rabcan511.11
Jozef Kostolny654.92