Paper Info
Title
Learning Interactions Between Cardiac Shape And Deformation: Application To Pulmonary Hypertension
Abstract
Cardiac shape and deformation are two relevant descriptors for the characterization of cardiovascular diseases. It is also known that strong interactions exist between them depending on the disease. In clinical routine, these high dimensional descriptors are reduced to scalar values (ventricular ejection fraction, volumes, global strains...), leading to a substantial loss of information. Methods exist to better integrate these high-dimensional data by reducing the dimension and mixing heterogeneous descriptors. Nevertheless, they usually do not consider the interactions between the descriptors. In this paper, we propose to apply dimensionality reduction on high dimensional cardiac shape and deformation descriptors and take into account their interactions. We investigated two unsupervised linear approaches, an individual analysis of each feature (Principal Component Analysis), and a joint analysis of both features (Partial Least Squares) and related their output to the main characteristics of the studied pathology. We experimented both methods on right ventricular meshes from a population of 254 cases tracked along the cycle (154 with pulmonary hypertension, 100 controls). Despite similarities in the output space obtained by the two methods, substantial differences are observed in the reconstructed shape and deformation patterns along the principal modes of variation, in particular in regions of interest for the studied disease.
Year
DOI
Venue
2019
10.1007/978-3-030-39074-7_13
STATISTICAL ATLASES AND COMPUTATIONAL MODELS OF THE HEART: MULTI-SEQUENCE CMR SEGMENTATION, CRT-EPIGGY AND LV FULL QUANTIFICATION CHALLENGES
DocType
Volume
ISSN
Conference
12009
0302-9743
Citations 
PageRank 
References 
0
0.34
0
Authors
4
Name
Order
Citations
PageRank
Maxime Di Folco100.34
P. Clarysse2384.15
Pamela Moceri300.68
N Duchateau419920.53