Title
A Coarse-to-fine Cascading Model for Cataract Nuclear Segmentation in Slit-lamp Photographs
Abstract
A nuclear cataract is an age-related chronic and priority ophthalmic disease in which a clouding of the lens in the human eye affects vision. Automatic segmentation of nuclear region based on slit-lamp photographs is a basic step for computer-aided diagnosis such as nuclear cataract grading. However, slit-lamp photographs collected from a clinic scenario often have complex background containing the eyelids, sclera and cornea with spectral highlights. The existing efforts using traditional image processing that have unsatisfactory results, and the deep learning method using standard Faster R-CNN tends to obtain a bigger nuclear contour. In this paper, we propose a coarse-to-fine deep learning solution to localize nuclear regions by cascading the Faster R-CNN in a two-stage framework. First, a nuclear ROI (region of interest) predictor is pre-trained to localize a rough position and remove complex backgrounds. Then, a fine nuclear locator is applied to predict a more compact nuclear bounding box. Finally, an ellipse-like nuclear contour is fitted based on its bounding box. Evaluated on a clinical dataset of 884 slit-lamp photographs, the proposed method outperforms the state-of-the-art, improving the overlapping rate (IoU) by 0.33% from 67.98% to 68.31%, and increasing the success rate by 2.55% from 85.71% to 88.26%.
Year
DOI
Venue
2019
10.1109/VCIP47243.2019.8965714
2019 IEEE Visual Communications and Image Processing (VCIP)
Keywords
Field
DocType
coarse-to-fine cascading model,cataract nuclear segmentation,age-related chronic,priority ophthalmic disease,nuclear region,nuclear cataract grading,complex background,bigger nuclear contour,coarse-to-fine deep learning solution,nuclear ROI,fine nuclear locator,compact nuclear bounding box,ellipse-like nuclear contour,slit-lamp photographs
Human eye,Computer vision,Computer science,Segmentation,Image processing,Nuclear cataract,Artificial intelligence,Deep learning,Region of interest,Slit lamp,Minimum bounding box
Conference
ISSN
ISBN
Citations 
1018-8770
978-1-7281-3724-7
0
PageRank 
References 
Authors
0.34
7
14
Name
Order
Citations
PageRank
Jun Wu100.34
Xianfang Rong200.34
Zhennan Zhao310.72
Lei Cai45319.97
Dayong Ding500.34
Xirong Li6119168.62
Zongjiang Shang711.39
Kaiwei Wang800.34
Xixi He921.09
Xiangjia Zhu1010.72
Wenwen He1110.72
Yi Lu1200.34
Keke Zhang1310.72
Yinglei Zhang1410.72