Title
Polar Labeling: Silver standard algorithm for training disease classifiers.
Abstract
Motivation: Expert-labeled data are essential to train phenotyping algorithms for cohort identification. However expert labeling is time and labor intensive, and the costs remain prohibitive for scaling phenotyping to wider use-cases. Results: We present an approach referred to as polar labeling (PL), to create silver standard for training machine learning (ML) for disease classification. We test the hypothesis that ML models trained on the silver standard created by applying PL on unlabeled patient records, are comparable in performance to the ML models trained on gold standard, created by clinical experts through manual review of patient records. We perform experimental validation using health records of 38 023 patients spanning six diseases. Our results demonstrate the superior performance of the proposed approach.
Year
DOI
Venue
2020
10.1093/bioinformatics/btaa088
BIOINFORMATICS
DocType
Volume
Issue
Journal
36
10
ISSN
Citations 
PageRank 
1367-4803
0
0.34
References 
Authors
0
4
Name
Order
Citations
PageRank
Kavishwar B. Wagholikar115116.63
Hossein Estiri283.94
Marykate Murphy300.34
Shawn N. Murphy469997.60