Paper Info
Title
Objective Assessment of Beat Quality in Transcranial Doppler Measurement of Blood Flow Velocity in Cerebral Arteries
Abstract
<italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Objective</italic> : Transcranial Doppler (TCD) ultrasonography measures pulsatile cerebral blood flow velocity in the arteries and veins of the head and neck. Similar to other real-time measurement modalities, especially in healthcare, the identification of high-quality signals is essential for clinical interpretation. Our goal is to identify poor quality beats and remove them prior to further analysis of the TCD signal. <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Methods</italic> : We selected objective features for this purpose including Euclidean distance between individual and average beat waveforms, cross-correlation between individual and average beat waveforms, ratio of the high-frequency power to the total beat power, beat length, and variance of the diastolic portion of the beat waveform. We developed an iterative outlier detection algorithm to identify and remove the beats that are different from others in a recording. Finally, we tested the algorithm on a dataset consisting of more than 15 h of TCD data recorded from 48 stroke and 34 in-hospital control subjects. <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Results</italic> : We assessed the performance of the algorithm in the improvement of estimation of clinically important TCD parameters by comparing them to that of manual beat annotation. The results show that there is a strong correlation between the two, that demonstrates the algorithm has successfully recovered the clinically important features. We obtained significant improvement in estimating the TCD parameters using the algorithm accepted beats compared to using all beats. <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Significance</italic> : Our algorithm provides a valuable tool to clinicians for automated detection of the reliable portion of the data. Moreover, it can be used as a pre-processing tool to improve the data quality for automated diagnosis of pathologic beat waveforms using machine learning.
Year
DOI
Venue
2020
10.1109/TBME.2019.2923146
IEEE Transactions on Biomedical Engineering
Keywords
Field
DocType
Signal processing algorithms,Euclidean distance,Arteries,Iterative algorithms,Correlation,Morphology
Anomaly detection,Computer vision,Data quality,Pulsatile flow,Blood flow,Computer science,Euclidean distance,Transcranial Doppler,Artificial intelligence,Cerebral blood flow,Beat (music)
Journal
Volume
Issue
ISSN
67
3
0018-9294
Citations 
PageRank 
References 
0
0.34
0
Authors
11
Name
Order
Citations
PageRank
Kian Jalaleddini1136.17
Nicolas Canac200.34
Samuel G. Thorpe300.34
Michael J. O’Brien400.34
Mina Ranjbaran500.34
Benjamin Delay600.34
Amber Y. Dorn700.34
Fabien Scalzo86815.42
Corey M. Thibeault9365.10
Seth J. Wilk1000.34
Robert Hamilton1121.05