Title
Ensemble learning for classifying single-cell data and projection across reference atlases.
Abstract
Single-cell data are being generated at an accelerating pace. How best to project data across single-cell atlases is an open problem. We developed a boosted learner that overcomes the greatest challenge with status quo classifiers: low sensitivity, especially when dealing with rare cell types. By comparing novel and published data from distinct scRNA-seq modalities that were acquired from the same tissues, we show that this approach preserves cell-type labels when mapping across diverse platforms.
Year
DOI
Venue
2020
10.1093/bioinformatics/btaa137
BIOINFORMATICS
DocType
Volume
Issue
Journal
36
11
ISSN
Citations 
PageRank 
1367-4803
0
0.34
References 
Authors
0
5
Name
Order
Citations
PageRank
Lin Wang100.34
Francisca Catalan200.34
Karin Shamardani300.34
Husam Babikir400.34
Aaron Diaz571.64