Title
Ec-Gan: Inferring Brain Effective Connectivity Via Generative Adversarial Networks
Abstract
Inferring effective connectivity between different brain regions from functional magnetic resonance imaging (fMRI) data is an important advanced study in neuroinformatics in recent years. However, current methods have limited usage in effective connectivity studies due to the high noise and small sample size of fMRI data. In this paper. we propose a novel framework for inferring effective connectivity based on generative adversarial networks (GAN), named as EC-GAN. The proposed framework EC-GAN infers effective connectivity via an adversarial process, in which we simultaneously train two models: a generator and a discriminator. The generator consists of a set of effective connectivity generators based on structural equation models which can generate the fMRI time series of each brain region via effective connectivity. Meanwhile, the discriminator is employed to distinguish between the joint distributions of the real and generated fMRI time series. Experimental results on simulated data show that EC-GAN can better infer effective connectivity compared to other state-of-the-art methods. The real-world experiments indicate that EC-GAN can provide a new and reliable perspective analyzing the effective connectivity of fMRI data.
Year
Venue
DocType
2020
THIRTY-FOURTH AAAI CONFERENCE ON ARTIFICIAL INTELLIGENCE, THE THIRTY-SECOND INNOVATIVE APPLICATIONS OF ARTIFICIAL INTELLIGENCE CONFERENCE AND THE TENTH AAAI SYMPOSIUM ON EDUCATIONAL ADVANCES IN ARTIFICIAL INTELLIGENCE
Conference
Volume
ISSN
Citations 
34
2159-5399
0
PageRank 
References 
Authors
0.34
0
6
Name
Order
Citations
PageRank
Jinduo Liu100.68
Junzhong Ji222229.30
Guangxu Xun310911.89
Liuyi Yao4125.00
Mengdi Huai52910.02
Aidong Zhang62970405.63