Title
Cardiac Resynchronization Guided by Ultra-High-Frequency ECG Maps
Abstract
Here we present a technique based on 14-lead ultrahigh-frequency electrocardiogram (UHF-ECG, 5 kHz) able to measure the immediate effect of cardiac resynchronization therapy (CRT) settings on electrical ventricular dyssynchrony.Resting UHF-ECGs were sequentially recorded during different CRT settings: CRT OFF, CRT ON, VV delays 0, -20, -40 ms, and SMART sensing (Boston Scientific) in 33 patients. Electrical depolarization maps were computed from signal-averaged UHF-ECGs in the frequency band 150-1000 Hz. The horizontal axis of each map indicates time and the vertical axis indicates the activation location (V1-V8 lead). The red areas show the location-time of the maximal volume of simultaneously depolarized myocardial cells.The optimal CRT setting is characterized by a narrow and vertical activation pattern. Optimal CRT setting selected by a physician from electrical depolarization maps corresponded to the minimal mechanical intraventricular delay obtained from echocardiography in 61% of patients; in 27% of patients the difference was within a 10 ms interval.UHF-ECG depolarization maps represent a useful tool for the selection and setting of optimal cardiac resynchronization therapy.
Year
DOI
Venue
2019
10.23919/CinC49843.2019.9005622
2019 Computing in Cardiology (CinC)
Keywords
DocType
ISSN
cardiac resynchronization,ultrahigh-frequency ECG,ultrahigh-frequency electrocardiogram,cardiac resynchronization therapy,electrical ventricular dyssynchrony,CRT OFF,VV delays,SMART sensing,electrical depolarization maps,frequency band,optimal CRT setting,minimal mechanical intraventricular delay,UHF-ECG depolarization maps,optimal cardiac resynchronization therapy,signal-averaged UHF-ECG,CRT settings,depolarized myocardial cells,frequency 150.0 Hz to 1000.0 Hz,frequency 5.0 kHz
Conference
2325-8861
ISBN
Citations 
PageRank 
978-1-7281-5942-3
0
0.34
References 
Authors
0
10
Name
Order
Citations
PageRank
Pavel Jurák1512.45
magdalena matejkova203.38
Halamek, J.339.72
Plesinger, F.438.70
ivo viscor545.53
V. Vondra623.27
Jolana Lipoldova702.03
Miroslav Novak801.69
Radovan Smisek900.34
P Leinveber1057.17