Abstract | ||
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Here we present a technique based on 14-lead ultrahigh-frequency electrocardiogram (UHF-ECG, 5 kHz) able to measure the immediate effect of cardiac resynchronization therapy (CRT) settings on electrical ventricular dyssynchrony.Resting UHF-ECGs were sequentially recorded during different CRT settings: CRT OFF, CRT ON, VV delays 0, -20, -40 ms, and SMART sensing (Boston Scientific) in 33 patients. Electrical depolarization maps were computed from signal-averaged UHF-ECGs in the frequency band 150-1000 Hz. The horizontal axis of each map indicates time and the vertical axis indicates the activation location (V1-V8 lead). The red areas show the location-time of the maximal volume of simultaneously depolarized myocardial cells.The optimal CRT setting is characterized by a narrow and vertical activation pattern. Optimal CRT setting selected by a physician from electrical depolarization maps corresponded to the minimal mechanical intraventricular delay obtained from echocardiography in 61% of patients; in 27% of patients the difference was within a 10 ms interval.UHF-ECG depolarization maps represent a useful tool for the selection and setting of optimal cardiac resynchronization therapy. |
Year | DOI | Venue |
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2019 | 10.23919/CinC49843.2019.9005622 | 2019 Computing in Cardiology (CinC) |
Keywords | DocType | ISSN |
cardiac resynchronization,ultrahigh-frequency ECG,ultrahigh-frequency electrocardiogram,cardiac resynchronization therapy,electrical ventricular dyssynchrony,CRT OFF,VV delays,SMART sensing,electrical depolarization maps,frequency band,optimal CRT setting,minimal mechanical intraventricular delay,UHF-ECG depolarization maps,optimal cardiac resynchronization therapy,signal-averaged UHF-ECG,CRT settings,depolarized myocardial cells,frequency 150.0 Hz to 1000.0 Hz,frequency 5.0 kHz | Conference | 2325-8861 |
ISBN | Citations | PageRank |
978-1-7281-5942-3 | 0 | 0.34 |
References | Authors | |
0 | 10 |
Name | Order | Citations | PageRank |
---|---|---|---|
Pavel Jurák | 1 | 5 | 12.45 |
magdalena matejkova | 2 | 0 | 3.38 |
Halamek, J. | 3 | 3 | 9.72 |
Plesinger, F. | 4 | 3 | 8.70 |
ivo viscor | 5 | 4 | 5.53 |
V. Vondra | 6 | 2 | 3.27 |
Jolana Lipoldova | 7 | 0 | 2.03 |
Miroslav Novak | 8 | 0 | 1.69 |
Radovan Smisek | 9 | 0 | 0.34 |
P Leinveber | 10 | 5 | 7.17 |