Title
QuartataWeb: integrated chemical-protein-pathway mapping for polypharmacology and chemogenomics.
Abstract
aSummary: QuartataWeb is a user-friendly server developed for polypharmacological and chemogenomics analyses. Users can easily obtain information on experimentally verified (known) and computationally predicted (new) interactions between 5494 drugs and 2807 human proteins in DrugBank, and between 315 514 chemicals and 9457 human proteins in the STITCH database. In addition, QuartataWeb links targets to KEGG pathways and GO annotations, completing the bridge from drugs/chemicals to function via protein targets and cellular pathways. It allows users to query a series of chemicals, drug combinations or multiple targets, to enable multi-drug, multi-target, multi-pathway analyses, toward facilitating the design of polypharmacological treatments for complex diseases.
Year
DOI
Venue
2020
10.1093/bioinformatics/btaa210
BIOINFORMATICS
DocType
Volume
Issue
Journal
36
12
ISSN
Citations 
PageRank 
1367-4803
0
0.34
References 
Authors
0
4
Name
Order
Citations
PageRank
Hongchun Li100.68
Fen Pei200.68
D Lansing Taylor300.34
Ivet Bahar436139.41