Title
Regenerative Semi-Supervised Bidirectional W-Network-Based Knee Bone Tumor Classification On Radiographs Guided By Three-Region Bone Segmentation
Abstract
The objective of this study is to develop and evaluate a new deep learning architecture, namely regenerative semi-supervised bidirectional W-network (RSS-BW), to predict the tumor state of the knee bone from radiographic images. First, we constructed an autoencoder model, called Bidirectional W-network (BW), for segmenting three-region (i.e., femur, tibia, and fibula) of knee bone. Using these regions as input data, RSS-BW architecture consisting of the autoencoding model for regenerating the bone structures, the backbone model for extracting features with pretrained ImageNet, and the predicting model for knee bone tumor classification are established. The developed scheme rapidly obtained segmentation results of the three-region of knee bone with a mean dice score of 98.06 +/- 0.08%. Moreover, two types of classification are conducted: single-step and double-step. The single-step classifies the bone images into normal, benign, and malignant states. The mean values of accuracy, precision, recall and F-beta score obtained from the segmented images were 85.23 +/- 3.91%, 82.23 +/- 3.22%, 82.15 +/- 3.31%, and 82.21 +/- 3.25%, respectively. For the double-step of bone tumor classification, the images are classified first as normal versus abnormal. The second classification is conducted for abnormal images as benign versus malignant. The double-step classification shows an improvement of the mean accuracy by 1.7% compared to the single-step classification. In conclusion, the RSS-BW model presents higher accuracy than conventional models, indicating its potential clinical decision support for bone tumor classification.
Year
DOI
Venue
2019
10.1109/ACCESS.2019.2949125
IEEE ACCESS
Keywords
DocType
Volume
Bone segmentation, bone tumor classification, bidirectional W-network, RSS-BW, radiography
Journal
7
ISSN
Citations 
PageRank 
2169-3536
0
0.34
References 
Authors
0
5
Name
Order
Citations
PageRank
Ngoc-Huynh Ho1103.51
Hyungjeong Yang245547.05
Soo-Hyung Kim319149.03
Sung Taek Jung400.34
Sang-Don Joo500.34