Title
Deep learning for mass detection in Full Field Digital Mammograms.
Abstract
In recent years, the use of Convolutional Neural Networks (CNNs) in medical imaging has shown improved performance in terms of mass detection and classification compared to current state-of-the-art methods. This paper proposes a fully automated framework to detect masses in Full-Field Digital Mammograms (FFDM). This is based on the Faster Region-based Convolutional Neural Network (Faster-RCNN) model and is applied for detecting masses in the large-scale OPTIMAM Mammography Image Database (OMI-DB), which consists of ∼80,000 FFDMs mainly from Hologic and General Electric (GE) scanners. This research is the first to benchmark the performance of deep learning on OMI-DB. The proposed framework obtained a True Positive Rate (TPR) of 0.93 at 0.78 False Positive per Image (FPI) on FFDMs from the Hologic scanner. Transfer learning is then used in the Faster R-CNN model trained on Hologic images to detect masses in smaller databases containing FFDMs from the GE scanner and another public dataset INbreast (Siemens scanner). The detection framework obtained a TPR of 0.91±0.06 at 1.69 FPI for images from the GE scanner and also showed higher performance compared to state-of-the-art methods on the INbreast dataset, obtaining a TPR of 0.99±0.03 at 1.17 FPI for malignant and 0.85±0.08 at 1.0 FPI for benign masses, showing the potential to be used as part of an advanced CAD system for breast cancer screening.
Year
DOI
Venue
2020
10.1016/j.compbiomed.2020.103774
Computers in Biology and Medicine
Keywords
DocType
Volume
Deep learning,CNN,Mammogram,FFDM,Mass detection
Journal
121
ISSN
Citations 
PageRank 
0010-4825
1
0.37
References 
Authors
0
5
Name
Order
Citations
PageRank
Richa Agarwal110.37
Oliver Díaz210.37
Moi Hoon Yap319027.82
Xavier Lladó410.37
Robert Martí510.37