Paper Info
Title
Dual Energy Differential Phase Contrast CT (DE-DPC-CT) Imaging
Abstract
When more than two elemental materials are present in a given object, material quantification may not be robust and accurate when the routine two-material decomposition scheme in current dual energy CT imaging is employed. In this work, we present an innovative scheme to accomplish accurate three-material decomposition with measurements from a dual energy differential phase contrast CT (DE-DPC-CT) acquisition. A DE-DPC-CT system was constructed using a grating interferometer and a photon counting CT imaging system with two energy bins. The DE-DPC-CT system can simultaneously measure both the imaginary and the real part of the complex refractive index to enable a three-material decomposition. Physical phantom with 21 material inserts were constructed and measured using DE-DPC-CT system. Results demonstrated excellent accuracy in elemental material quantification. For example, relative root-mean-square errors of 4.5% for calcium and 5.2% for iodine were achieved using the proposed three-material decomposition scheme. Biological tissues with iodine inserts were used to demonstrate the potential utility of the proposed spectral CT imaging method. Experimental results showed that the proposed method correctly differentiates the bony structure, iodine, and the soft tissue in the biological specimen samples. A triple spectra CT scan was also performed to benchmark the performance of the DE-DPC-CT scan. Results demonstrated that the material decomposition from the DE-DPC-CT has a much lower quantification noise than that from the triple spectra CT scan.
Year
DOI
Venue
2020
10.1109/TMI.2020.2990347
IEEE Transactions on Medical Imaging
Keywords
DocType
Volume
Contrast Media,Phantoms, Imaging,Photons,Tomography, X-Ray Computed
Journal
39
Issue
ISSN
Citations 
11
0278-0062
0
PageRank 
References 
Authors
0.34
0
4
Name
Order
Citations
PageRank
Xu Ji100.68
Ran Zhang200.68
Ke Li310.69
Guang-Hong Chen4152.88