Title
DCSA: Distributed Channel-Storage Architecture for Flow-Based Microfluidic Biochips
Abstract
Flow-based microfluidic biochips have attracted much attention in the EDA community due to their miniaturized size and execution efficiency. Previous research, however, still follows the traditional computing model with a dedicated storage unit, which actually becomes a bottleneck of the performance of biochips. In this article, we propose a distributed channel-storage architecture (DCSA) to cache fluid samples inside flow channels temporarily. Since distributed storage can be accessed more efficiently than a dedicated storage unit and channels can switch between the roles of transportation and storage easily, biochips with this architecture can achieve a higher execution efficiency even with fewer resources. Furthermore, we also address the flow-path planning that enables the manipulation of actual fluid transportation/caching on a chip. The simulation results confirm that the execution efficiency of a bioassay can be improved significantly, while the number of valves in the biochip can be reduced accordingly. Also, flow paths for transportation tasks can be constructed and planned automatically with minimum extra resources.
Year
DOI
Venue
2021
10.1109/TCAD.2020.2994267
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Keywords
DocType
Volume
Architectural synthesis,channel storage,flow-path mapping,microfluidic biochips,scheduling
Journal
40
Issue
ISSN
Citations 
1
0278-0070
2
PageRank 
References 
Authors
0.38
14
7
Name
Order
Citations
PageRank
Chunfeng Liu1173.09
Xing Huang2417.17
Bing Li317233.77
Hailong Yao426739.56
Zongren Peng520.72
Tsung-Yi Ho65921.63
Ulf Schlichtmann710921.56