Title
A Parabolic Free Boundary Problem Arising In A Model Of Cell Polarization
Abstract
The amplification of an external signal is a key step in direction sensing of biological cells. We consider a simple model for the response to a time-depending signal, which was previously proposed by the last three authors. The model consists of a bulk-surface reaction-diffusion model. We prove that in a suitable asymptotic limit the system converges to a bulk-surface parabolic obstacle-type problem. For this model and a reduction to a nonlocal surface equation we show an L-1-contraction property and, in the case of time-constant signals, the stability of stationary states.
Year
DOI
Venue
2021
10.1137/20M1349114
SIAM JOURNAL ON MATHEMATICAL ANALYSIS
Keywords
DocType
Volume
PDEs on surfaces, obstacle-type problem, stability of steady states
Journal
53
Issue
ISSN
Citations 
1
0036-1410
0
PageRank 
References 
Authors
0.34
0
4
Name
Order
Citations
PageRank
Anna Logioti100.34
BARBARA NIETHAMMER2155.87
Matthias Röger362.49
J. J. L. Velázquez4138.41