Paper Info
Title
Oxygen extraction fraction mapping with multi-parametric quantitative BOLD MRI: reduced transverse relaxation bias using 3D-GraSE imaging.
Abstract
Magnetic resonance imaging (MRI)-based quantification of the blood-oxygenation-level-dependent (BOLD) effect allows oxygen extraction fraction (OEF) mapping. The multi-parametric quantitative BOLD (mq-BOLD) technique facilitates relative OEF (rOEF) measurements with whole brain coverage in clinically applicable scan times. Mq-BOLD requires three separate scans of cerebral blood volume and transverse relaxation rates measured by gradient-echo (1/T2∗) and spin-echo (1/T2). Although the current method is of clinical merit in patients with stroke, glioma and internal carotid artery stenosis (ICAS), there are relaxation measurement artefacts that impede the sensitivity of mq-BOLD and artificially elevate reported rOEF values.
Year
DOI
Venue
2020
10.1016/j.neuroimage.2020.117095
NeuroImage
Keywords
DocType
Volume
Oxygen extraction fraction OEF,Multi-parametric quantitative BOLD,mq-BOLD,T2,R2’,3D GraSE
Journal
220
ISSN
Citations 
PageRank 
1053-8119
0
0.34
References 
Authors
0
3
Name
Order
Citations
PageRank
Stephan Kaczmarz101.01
Fahmeed Hyder2429.53
Christine Preibisch332.41